新研究证实对男性后生的影响

作者: Hibz Y.D.

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根据发表在FASEB周报上的一项取而代之研究工作，也似乎对男同性恋卵子消除有害效用。

一项本意在于提高男同性恋受孕的研究工作发掘出一种是从CB2的伦蛋白与卵子生成的过程有关。研究工作人员推论却说，这一发掘出表明，似乎会损害男同性恋的受孕。

由意大利罗马大学Paola Grimaldi领导的研究工作制作团队让实验大鼠服食不同的药物，其中一组服食CB2蛋白的活化剂，另一组则服食CB2蛋白抑制，MLT-作为样本只服食生理盐水。研究工作得出，服食CB2活化剂的大鼠有来得快的生精速所部，而服食CB2抑制的大鼠则显示了相反的精准度并有速度慢的卵子消除所部。这些得出，CB2的激活并不需要维持一定的平衡状态以应有应该的卵子消除过程。

FASEB周报的编委Thoru Pederson反驳，这项研究工作不太似乎为男同性恋不育症的治疗开辟取而代之的研究工作侧向。他还却说：“内源性伦对卵子正常消除会有正面精准度，如果使用可以进一步促使这种精准度的激动剂，不太似乎发展出治疗男同性恋不育症的一些取而代之疗法”。

Marijuana Can Affect Male Fertility, Suggests New Study

The study focusing mainly on finding ways to enhance male fertility has found that a ‘marijuana receptor’ called CB2 (a cannabinoid receptor) is linked with the regulation of sperm production (a process named spermatogenesis). This might sound like good news, but the researchers of the study explain that this finding indicates that marijuana might thus be disrupting male fertility.

Led by Paola Grimaldi from the University of Rome Tor Vergata, Italy, the team treated mice with different agents: one group, with an activator of the CB2 receptor; another with an inhibitor of the same receptor; a third group acting as the control one received only a saline solution.

The findings show that the CB2 activator group had a more rapid rate of spermatogenesis while the inhibitor group displayed the opposite effect as they had a slower rate of sperm production. These results suggest that CB2 activation is needed to be in a certain balance for spermatogenesis to occur properly and adequately.

This research might be opening up new doors for the treatment of male infertility, as pointed out by the Editor-in-Chief of The FASEB Journal, Thoru Pederson. According to the latter, “the normal beneficial effects of endogenous cannabinoids on spermatogenesis can be stimulated further by a chemical mimic, an agonist, is a potentially promising new idea for treating male infertility“.

（撰文来自沈阳山阳家圆医院官方网站）